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Single base mutations in the nucleocapsid gene of SARS-CoV-2 affects amplification efficiency of sequence variants and may lead to assay failure

Storey N., Brown J.R., Pereira R.P.A., O'Sullivan D.M., Huggett J.F., Williams R., Breuer J., Harris K.A.
Keywords:

SARS-CoV-2, Nucleocapsid, Mutations, PCR, Failure, Silico

Document type Article
Journal title / Source Journal of Clinical Virology Plus
Volume 1
Issue 3
Page numbers / Article number 100037
Publisher's name Elsevier BV
Publication date 2021-9
ISSN 2667-0380
DOI 10.1016/j.jcvp.2021.100037
Web URL https://www.sciencedirect.com/science/article/pii/S2667038021000296
Language English

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Information

Project title (JRP)
18HLT03: SEPTIMET: Metrology to enable rapid and accurate clinical measurements in acute management of sepsis
Name of Call / Funding Programme
EMPIR 2018: Health