Improved traceability chain of nanoparticle size measurements

Short Name: nPSize, Project Number: 17NRM04
Scientist holding a red transparent pill

Improving nanoparticle size measurement accuracy for safety assessment


Nanomaterials and nanoparticles are finding applications across a wide range of technology sectors, from medicine and food to transportation and construction. In order to assess these new materials for potential risks to health and the environment, they need to be well-characterised: from the range of measurements possible, constituent nanoparticle size, shape, and size distribution are important factors for the risk evaluation process.

 

This project assessed a range of nanoparticle measurement systems, including Scanning Electron Microscopy and Small Angle X-ray Scattering, and delivered to users improved calibration methods. For the techniques under investigation, physical models of their response to a range of nanoparticle types were developed; validated reference materials were also used for an inter-comparison of measurement systems, with an evaluation of associated measurement accuracies. With project contributions to standards development work, manufacturers will be better placed to assess the human and environmental risks posed by nanomaterials across a whole range of products.

Project website
Publications
nPSize VSL images as 2D arrays
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Zenodo Repository

nPSize LNE images as 2D arrays
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Zenodo Repository

nPSize CEA images as 2D arrays
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Zenodo Repository

nPSize02_AFM_SMD
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Zenodo Repository

nPSize BAM images as 2D arrays
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Zenodo Repository

npSize_SAXS_data_PTB
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Zenodo Repository

Other Participants
Commissariat à l'énergie atomique et aux énergies alternatives (France)
DIN Deutsches Institut für Normung e. V. (Germany)
POLLEN Metrology (France)
Università degli Studi di Torino (Italy)